Rational use of regional nodal irradiation needed

Whole breast and regional nodal irradiation in prone versus supine position in left sided breast cancer

BACKGROUND Prone whole breast irradiation (WBI) leads to reduced heart and lung doses in breast cancer patients receiving adjuvant radiotherapy. In this feasibility trial, we investigated the prone position for whole breast + lymph node irradiation (WB + LNI). METHODS A new support device was developed for optimal target coverage, on which patients are positioned in a position resembling a ph...

Evaluation of regional nodes irradiation during breast cancer radiotherapy

Background: The purpose of this study was to evaluate nodal irradiation with conventional three-field's technique. Materials and Methods: Fifty patients with breast cancer were enrolled in this study. Computed tomography scans in the supine treatment position were imported into a treatment planning system. Levels I-III axillary and supraclavicular nodes were identified and their depths to the a...

Access and Rational use of Plasma Protein Therapies (PPTs)

adjuvant regional nodal irradiation recommendations after acosog z0011 (alliance) trial results: “our doubts and uncertainties maybe traitors for undertreated patients”

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Patterns of practice of regional nodal irradiation in breast cancer: results of the European Organization for Research and Treatment of Cancer (EORTC) NOdal Radiotherapy (NORA) survey.

BACKGROUND Predicting outcome of breast cancer (BC) patients based on sentinel lymph node (SLN) status without axillary lymph node dissection (ALND) is an area of uncertainty. It influences the decision-making for regional nodal irradiation (RNI). The aim of the NORA (NOdal RAdiotherapy) survey was to examine the patterns of RNI. METHODS A web-questionnaire, including several clinical scenari...